alfashimi.com
plant tissue culture media and biochemicals | |
|
|
Thiamine hydrochloride | T0614 |
Safety Data Sheet | |
according to Regulation (EU) 2015/830 | Version: 2.1 |
Date of issue: 15/04/2011Revision date 24/01/2019 |
|
Supersedes 25/09/2017 |
|
|
|
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1. | Product identifier |
|
Product form | : Substance | |
Trade name | : Thiamine hydrochloride | |
EC-No. |
| : 200-641-8 |
CAS-No. | : 67-03-8 | |
REACH registration No | : 01-2120773699-31-xxxx | |
Product code | : T0614 | |
Formula | : C12H17ClN4OS · HCl | |
1.2. Relevant identified uses of the substance or mixture and uses advised against
1.2.1. Relevant identified uses
Main use category : Professional use
Industrial/Professional use spec : For professional use only. Duchefa Biochemie B.V. products are intended
only for "in vitro laboratory" research purposes.
1.2.2. Uses advised against
No additional information available
1.3. Details of the supplier of the safety data sheet
Supplier
Duchefa Biochemie B.V.
A. Hofmanweg 71
2031 BH Haarlem - The Netherlands
T +31(0)23-5319093 - F +31(0)23-5318027
1.4. | Emergency telephone number |
|
|
Emergency number | : Supplier contact information: | ||
|
| +31(0)23-5319093 | (M-F 09:00-17:00) |
|
| +31(0)6-30109355 | (outside office hours) |
Organisation/Company | Address | Comment |
World Health Organization world | http://apps.who.int/poisoncentres/ | Consult website for a local poison centre |
directory of poison centres |
|
|
SECTION 2: Hazards identification
2.1. | Classification of the substance or mixture |
|
Classification according to Regulation (EC) No. 1272/2008 [CLP] |
| |
Serious eye damage/eye irritation, Category 2 | H319 | |
Full text of H statements : see section 16 |
| |
Adverse physicochemical, human health and environmental effects
No additional information available
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 1/8
T0614 |
Safety Data Sheet
according to Regulation (EU) 2015/830
2.2. Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Hazard pictograms (CLP)
Signal word (CLP)
Hazard statements (CLP)
Precautionary statements (CLP)
2.3. Other hazards
Other hazards not contributing to the classification
:
GHS07
P305+P351 - IF IN EYES: Rinse cautiously with water for several minutes.
P337+P313 - If eye irritation persists: Get medical advice/attention.
SECTION 3: Composition/information on ingredients
3.1. Substances |
|
|
Name | : Thiamine hydrochloride | |
CAS-No. | : | 67-03-8 |
EC-No. | : | 200-641-8 |
Name | Product identifier | % |
Thiamine hydrochloride | (CAS-No.) 67-03-8 | >= 98,5 |
| (EC-No.) 200-641-8 |
|
Full text of H-statements: see section 16
3.2. Mixtures
Not applicable
SECTION 4: First aid measures
4.1. De script ion of first aid measures
First-aid measures general
First-aid measures after inhalation
First-aid measures after skin contact
First-aid measures after eye contact
First-aid measures after ingestion
Remove contact lenses, if present and easy to do. Continue rinsing.
4.2. Most important symptoms and effects, both acute and delay ed
Symptoms/effects : Gastrointestinal complaints.
4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 2/8
T0614 | ||
Safety Data Sheet |
| |
according to Regulation (EU) 2015/830 |
| |
| ||
SECTION 5: Firefighting measures | ||
5.1. | Extinguishing media |
|
Suitable extinguishing media | : Water | |
|
| Foam. |
5.2. | Special hazards arising from the substance or mixture | |
Hazardous decomposition products in | : - SOx | |
case of fire | Corrosive vapours | |
|
| Carbon oxides (CO, CO2) |
|
| - NOx. |
5.3. | Advice for firefighters |
|
Protection during firefighting | : Wear proper protective equipment. Self-contained breathing apparatus. | |
Other information | : Prevent fire fighting water from entering the environment. | |
SECTION 6: Accidental release measures | ||
6.1. | Personal precautions, protective equipment and emergency procedures | |
6.1.1. For non-emergency personnel | ||
Protective equipment | : Wear suitable protective clothing. | |
Measures in case of dust release | : Avoid dust formation. | |
6.1.2. For emergency responders |
| |
No additional information available |
| |
6.2. | Environmental precautions |
|
Prevent product from entering drains. |
| |
6.3. | Methods and material for containment and cleaning up | |
Methods for cleaning up | : Sweep up, shovel or vacuum. This material and its container must be | |
|
| disposed of in a safe way, and as per local legislation. |
6.4. | Reference to other sections |
|
Reference to other sections (8, 13).
SECTION 7: Handling and storage
7.1. Precautions for safe handling
No additional information available
7.2. Conditions for safe storage, including any incompatibilities
Storage conditions : Keep container tightly closed and dry
Store at room temperature.
7.3. Specific end use(s)
For professional use only. Duchefa Biochemie B.V. products are intended only for "in vitro laboratory" research purposes.
SECTION 8: Exposure controls/personal protection
8.1. Control parameters
No additional information available
8.2. Exposure controls
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 3/8
|
|
| T0614 | |||
Safety Data Sheet |
|
|
|
| ||
according to Regulation (EU) 2015/830 |
|
|
|
| ||
|
|
|
|
|
|
|
Hand protection: |
|
|
|
|
| |
|
|
|
|
|
|
|
Type |
| Material | Permeation | Thickness (mm) | Standard |
|
|
|
|
|
|
|
|
Gloves |
| Nitrile rubber (NBR) | 6 (> 480 minutes) | 0,11 | EN 374 |
|
|
|
|
|
|
|
|
Eye protection:
Safety glasses (to European standard EN 166 or equivalent)
Skin and body protection:
Long sleeved protective clothing
Respiratory protection:
Dust production: dust mask with filter type P1
SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties
Physical state | : Solid | |
Appearance | : Powder. | |
Molecular mass | : 337,3 g/mol | |
Colour |
| : White to off-white. |
Odour |
| : Characteristic. |
Odour threshold | : No data available | |
pH |
| : 2,7 - 3,3 (2,5%) |
Relative evaporation rate (butylacetate=1) | : No data available | |
Melting point | : 248 - 250 °C | |
Freezing point | : No data available | |
Boiling point | : No data available | |
Flash point | : No data available | |
Auto-ignition temperature | : No data available | |
Decomposition temperature | : No data available | |
Flammability (solid, gas) | : No data available | |
Vapour pressure | : No data available | |
Relative vapour density at 20 °C | : No data available | |
Relative density | : 0,4 g/cm3 | |
Solubility | : Readily soluble in water. | |
|
| Water: ≈ 1000 g/l |
Log Pow | : No data available | |
Viscosity, kinematic | : No data available | |
Viscosity, dynamic | : No data available | |
Explosive properties | : No data available | |
Oxidising properties | : No data available | |
Explosive limit s | : No data available | |
9.2. | Other information |
|
No additional information available
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 4/8
T0614 |
Safety Data Sheet
according to Regulation (EU) 2015/830
SECTION 10: Stability and reactivity
10.1. Reactivity
Stable under normal conditions.
10.2. Chemical stability
Stable under normal conditions.
10.3. Possibility of hazardous reactions
Potential dust explosion hazard.
10.4. Conditions to avoid
- Heat
Water, humidity.
10.5. Incompatible materials
Bases
10.6. Hazardous decomposition products
Hydrogen chloride
Nitrogen oxides
- SOx.
SECTION 11: Toxicological information
11.1. | Information on toxicological effects | ||
Acute toxicity | : Not classified | ||
|
|
| |
Thiamine hydrochloride (67-03-8) |
|
| |
|
|
| |
LD50 oral rat |
| 3710 mg/kg | |
LD50 oral |
| 8224 mg/kg (mouse) | |
Skin corrosion/irritation | : Slightly irritating to the skin | ||
|
|
| pH: 2,7 - 3,3 (2,5%) |
Serious eye damage/irritation | : May cause eye irritation. | ||
|
|
| pH: 2,7 - 3,3 (2,5%) |
Respiratory or skin sensitisation | : Not classified | ||
Germ cell mutagenicity | : Not classified | ||
Carcinogenicity | : Not classified | ||
Reproductive toxicity | : Not classified | ||
STOT-single exposure | : Not classified | ||
STOT-repeated exposure | : Not classified | ||
Aspiration hazard | : Not classified | ||
Other information | : See actual entry in RTECS for complete information: XI7350000. | ||
SECTION 12: Ecological information | |||
12.1. | Toxicity |
|
|
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 5/8
T0614 | ||||
Safety Data Sheet |
|
| ||
according to Regulation (EU) 2015/830 |
|
| ||
|
|
|
| |
|
|
|
| |
| Thiamine hydrochloride (67-03-8) |
|
| |
| LC50 fish 1 | > 100 mg/l Oncorhynchus mykiss (Rainbow trout) |
| |
| EC50 Daphnia 1 | > 100 mg/l (Daphnia Magna) |
| |
12.2. | Persistence and degradability |
|
| |
|
|
|
| |
| Thiamine hydrochloride (67-03-8) |
|
| |
| Persistence and degradability | Product is biodegradable. |
| |
| Biodegradation | 74 % (7d) |
| |
12.3. | Bioaccumulative potential |
|
| |
| No additional information available |
|
| |
12.4. | Mobility in soil |
|
| |
| No additional information available |
|
| |
12.5. result s of PBT and vPvB assessment
No additional information available
12.6. Other adverse effects
No additional information available
SECTION 13: Disposal considerations
13.1. | Waste treatment methods |
|
|
Waste treatment methods | : This product is not hazardous. |
| |
Sewage disposal recommendations | : Disposal must be done according to official regulations. | ||
Product/Packaging disposal | : When not empty dispose of this container at hazardous or special waste | ||
recommendations | collection point. |
| |
Ecology - waste materials | : Avoid release to the environment. |
| |
SECTION 14: Transport information |
| ||
In accordance with ADR / IATA / IMDG |
|
| |
|
|
|
|
ADR |
| IMDG | IATA |
14.1. | UN number |
|
|
Not applicable | Not applicable | Not applicable | |
|
|
|
|
14.2. | UN proper shipping name |
|
|
Not applicable | Not applicable | Not applicable | |
|
|
| |
Not applicable | Not applicable | Not applicable | |
|
|
|
|
14.3. | Transport hazard class(es) |
|
|
Not applicable | Not applicable | Not applicable | |
|
|
| |
Not applicable | Not applicable | Not applicable | |
|
|
|
|
14.4. | Packing group |
|
|
Not applicable | Not applicable | Not applicable | |
|
|
|
|
14.5. | Environmental hazards |
|
|
Not applicable | Not applicable | Not applicable | |
|
|
|
|
No supplementary information available
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 6/8
T0614 |
Safety Data Sheet
according to Regulation (EU) 2015/830
14.6. Special precautions for user
Not applicable
14.7. Transport in bulk according to Annex II of Marpol and the IBC Code
Not applicable
SECTION 15: Regulatory information
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1. EU-Regulations
No REACH Annex XVII restrictions
Thiamine hydrochloride is not on the REACH Candidate List
Thiamine hydrochloride is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
Reference to AwSV
12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV
Netherlands
SZW-lijst van kankerverwekkende stoffen : The substance is not listed
SZW-lijst van mutagene stoffen : The substance is not listed
NIET- limit atieve lijst van voor de voortplanting giftige stoffen – Borstvoeding : The substance is not listed
NIET- limit atieve lijst van voor de voortplanting giftige stoffen – : The substance is not listed
Vruchtbaarheid
NIET- limit atieve lijst van voor de voortplanting giftige stoffen – Ontwikkeling : The substance is not listed
15.2. Chemical safety assessment
No additional information available
SECTION 16: Other information
Indication of changes:
1.1 | REACH registration No | Added |
|
2.1 | Classification according to Regulation | Added | Change from no classification to |
| (EC) No. 1272/2008 [CLP] |
| H319 (Eye cat.2) based on new |
|
|
| data from manufacturer. |
2.2 | Hazard pictograms (CLP) | Added | GHS07 |
2.2 | Signal word (CLP) | Added | Warning |
2.2 | Precautionary statements (CLP) | Added | P280;P305+P351;P337+P313 |
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 7/8
T0614 | ||||
Safety Data Sheet |
|
| ||
according to Regulation (EU) 2015/830 |
|
| ||
|
|
|
|
|
| Abbreviations and acronyms: |
|
| |
| ATE | Acute Toxicity Estimate |
|
|
| ADR | European Agreement concerning the International Carriage of Dangerous Goods by Road |
|
|
| BCF | Bioconcentration factor |
|
|
| CLP | Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008 |
|
|
| DPD | Dangerous Preparations Directive 1999/45/EC |
|
|
| DSD | Dangerous Substances Directive 67/548/EEC |
|
|
| IATA | International Air Transport Association |
|
|
| IMDG | International Maritime Dangerous Goods |
|
|
| LC50 | Median lethal concentration |
|
|
| LD50 | Median lethal dose |
|
|
| LOAEL | Lowest Observed Adverse Effect Level |
|
|
| NOAEC | No-Observed Adverse Effect Concentration |
|
|
| PBT | Persistent Bioaccumulative Toxic |
|
|
| REACH | Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation (EC) No 1907/2006 |
| |
| SDS | Safety Data Sheet |
|
|
| Data sources | : REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT | ||
|
| AND OF THE COUNCIL of 16 December 2008 on classification, labelling | ||
|
| and packaging of substances and mixtures, amending and repealing | ||
|
| Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No | ||
|
| 1907/2006. Supplier. |
|
|
Full text of H- and EUH-statements:
Eye Irrit. 2 | Serious eye damage/eye irritation, Category 2 |
H319 | Causes serious eye irritation. |
SDS Biochemicals version 2019
This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product
24/01/2019 Duchefa Biochemie B.V. EN (English) SDS Ref.: T0614 8/8
تیامین هیدروکلراید دوخفا, THIAMINE HCL Duchefa
تومان
میواینوزیتول دوخفا,MYO-INOSITOL duchefa
تومان
نیکوتینیک اسید دوخفا(NICOTINIC ACID duchefa)
تومان
FENAEDTA,E0509
تومان
.png)
.png)
