FE-EDDHA دوخفا
FE-EDDHA دوخفا
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plant tissue culture media and biochemicals






Safety Data Sheet                                                                       






SECTION 1: Identification of the substance/mixture and of the company/undertaking

    1. Product identifier

Product form                                        : Substance

Substance name                                   : Ferric-EDDHA

EC-No.                                                 : 283-044-5

CAS-No.                                              : 84539-55-9

REACH registration No                         : 01-2119487279-21

Product code                                       : F0527

Synonyms                                            : Ethylenediamine Dihydroxyphenyl acetate ferric


    1. Relevant identified uses of the substance or mixture and uses advised against
      1. Relevant identified uses

Main use category                                : Professional use

Industrial/Professional use spec            : For professional use only. Duchefa Biochemie B.V. products are intended

only for "in vitro laboratory" research purposes.


      1. Uses advised against

No additional information available


    1. Details of the supplier of the safety data sheet

Duchefa Biochemie B.V.

A. Hofmanweg 71

2031 BH Haarlem - The Netherlands

T +31(0)23-5319093 - F +31(0)23-5318027


    1. Emergency telephone number

Emergency number                                                      : Supplier contact information:

+31(0)23-5319093 (M-F 09:00-17:00)

+31(0)6-30109355 (outside office hours)





World Health Organization world directory of poison centres

Consult website for a local poison centre


SECTION 2: Hazards identification                                                                                    

    1. Classification of the substance or mixture

Classification according to Regulation (EC) No. 1272/2008 [CLP]

Not classified


Adverse physicochemical, human health and environmental effects

No additional information available

    1. Label elements

Labelling according to Regulation (EC) No. 1272/2008 [CLP]


No labelling applicable



    1. Other hazards

No additional information available


SECTION 3: Composition/information on ingredients                                                       

    1. Substances



Product identifier



(CAS-No.) 84539-55-9

(EC-No.) 283-044-5

(REACH-no) 01-2119487279-21



Full text of H-statements: see section 16


    1. Mixtures

Not applicable


SECTION 4: First aid measures                                                                                         

    1. Description of first aid measures


First-aid measures general                    : Seek medical attention if ill effect or irritation develops. First-aid measures after inhalation   : Assure fresh air breathing.

First-aid measures after skin contact     : Wash skin with mild soap and water. First-aid measures after eye contact      : Rinse with water.

First-aid measures after ingestion          : Rinse mouth out with water

Drink plenty of water

Do NOT induce vomiting.


    1. Most important symptoms and effects, both acute and delayed

No additional information available


    1. Indication of any immediate medical attention and special treatment needed

No additional information available


SECTION 5: Firefighting measures                                                                                    

    1. Extinguishing media

Suitable extinguishing media                 : Dry powder

Alcohol resistant foam. Water spray.

Unsuitable extinguishing media             : Carbon dioxide (CO2). Strong water jet.

    1. Special hazards arising from the substance or mixture


Hazardous decomposition products in case of fire




    1. Advice for firefighters

: Thermal decomposition generates :

      • COx
      • NOx
      • SOx.


Firefighting instructions                         : Prevent fire fighting water from entering the environment.

Protection during firefighting                 : Do not enter fire area without proper protective equipment, including

respiratory protection.



SECTION 6: Accidental release measures                                                                          

    1. Personal precautions, protective equipment and emergency procedures

General measures                                 : Spill should be handled by trained cleaning personnel properly equipped

with respiratory and eye protection.


      1. For non-emergency personnel

Protective equipment                            : Wear recommended personal protective equipment. Measures in case of dust release          : Avoid dust formation.

      1. For emergency responders

No additional information available


    1. Environmental precautions

Prevent entry to sewers and public waters. Avoid release to the environment.


    1. Methods and material for containment and cleaning up

Methods for cleaning up                       : Sweep up dry powder and dispose properly.

    1. Reference to other sections

No additional information available


SECTION 7: Handling and storage                                                                                     

    1. Precautions for safe handling

Precautions for safe handling                : Ensure good ventilation of the work station. Handle in accordance with good

industrial hygiene and safety procedures. Avoid dust formation.

    1. Conditions for safe storage, including any incompatibilities

Storage conditions                               : Store in dry, well-ventilated area Keep container tightly closed.

Store at room temperature.

    1. Specific end use(s)

For professional use only. Duchefa Biochemie B.V. products are intended only for "in vitro laboratory" research purposes.


SECTION 8: Exposure controls/personal protection                                                          

    1. Control parameters


Ferric-EDDHA (84539-55-9)

DNEL/DMEL (Workers)

Long-term - systemic effects, dermal

0,8 mg/kg bodyweight/day

Long-term - systemic effects, inhalation

1,8 mg/m³

DNEL/DMEL (General population)

Long-term - systemic effects,oral

125 mg/kg bodyweight/day

Long-term - systemic effects, inhalation

435 mg/m³

Long-term - systemic effects, dermal

417 mg/kg bodyweight/day

PNEC (Water)

PNEC aqua (freshwater)

2,4 mg/l

PNEC aqua (marine water)

0,24 mg/l

PNEC aqua (intermittent, freshwater)

1,2 mg/l

PNEC (Sediment)

PNEC sediment (freshwater)

1,9 mg/kg dwt

PNEC sediment (marine water)

0,19 mg/kg dwt

PNEC (Soil)



Ferric-EDDHA (84539-55-9)

PNEC soil

1,6 mg/kg dwt


PNEC sewage treatment plant

45 mg/l




Thickness (mm)



Nitrile rubber (NBR)

6 (> 480 minutes)


EN 374




Exposure controls Hand protection:




Eye protection:

Safety glasses (to European standard EN 166 or equivalent)

Skin and body protection:

Wear suitable protective clothing

Respiratory protection:

Dust production: dust mask with filter type P1


SECTION 9: Physical and chemical properties                                                                  

    1. Information on basic physical and chemical properties

Physical state                                                          : Solid

Appearance                                                             : Powder.

Colour                                                                     : Black



Odour                                                                     : Weak.

Odour threshold                                                       :  No data available

pH                                                                          :  No data available

pH solution                                                              : 8 - 9 10 g/l

Relative evaporation rate (butylacetate=1)                 : No data available


Melting point                                                           : > 500 °C (1.013 hPa)

Freezing point                                                          :  No data available

Boiling point                                                            :  No data available

Flash point                                                              :  No data available

Auto-ignition temperature                                         :  No data available

Decomposition temperature                                      : 270 °C

Flammability (solid, gas)                                          :  No data available

Vapour pressure                                                      :  No data available

Relative vapour density at 20 °C                               :  No data available

Relative density                                                       :  No data available

Density                                                                   : 1,5892 g/cm³ (at 20 °C)

Solubility                                                                 : Water: 150 - 203 g/l (at 23 °C)


Log Pow                                                                 : No data available

Log Kow                                                                 : -4,2 (at 23 °C)

Viscosity, kinematic                                                 :  No data available

Viscosity, dynamic                                                  :  No data available

Explosive properties                                                :  No data available

Oxidising properties                                                 :  No data available



Explosive limits                                                       : No data available


    1. Other information

Bulk density                                         : 600 - 800 kg/m³


SECTION 10: Stability and reactivity                                                                                  

    1. Reactivity

No additional information available

    1. Chemical stability

Stable under normal conditions.

    1. Possibility of hazardous reactions

No additional information available

    1. Conditions to avoid

High temperature Moisture.

    1. Incompatible materials

Strong oxidizers Strong bases.

    1. Hazardous decomposition products

When heated to decomposition, emits dangerous fumes:

  • COx
  • NOx
  • SOx.


SECTION 11: Toxicological information                                                                            

11.1.     Information on toxicological effects

Acute toxicity                                       :  Not classified


Ferric-EDDHA (84539-55-9)

LD50 oral rat

> 2000 mg/kg

LD50 dermal rat

> 2000 mg/kg

LC50 inhalation rat (mg/l)

> 4,2 mg/l/4h

Skin corrosion/irritation                         : Not classified Serious eye damage/irritation : Not classified Respiratory or skin sensitisation      : Not classified Germ cell mutagenicity          :  Not classified

Carcinogenicity                                     :  Not classified


Reproductive toxicity                            :  Not classified

STOT-single exposure                           :  Not classified

STOT-repeated exposure                      :  Not classified


Aspiration hazard                                  :  Not classified



SECTION 12: Ecological information                                                                                 

    1. Toxicity


Ferric-EDDHA (84539-55-9)

LC50 fish 1

> 120 mg/l Brachydanio rerio (zebra-fish)


    1. Persistence and degradability


Ferric-EDDHA (84539-55-9)

Persistence and degradability

Minimally biodegradable.


    1. Bioaccumulative potential

Ferric-EDDHA (84539-55-9)

Log Kow

-4,2 (at 23 °C)


    1. Mobility in soil

No additional information available


    1. results of PBT and vPvB assessment

No additional information available


    1. Other adverse effects

Additional information                           : Avoid release to the environment. Prevent entry to sewers and public waters

SECTION 13: Disposal considerations                                                                               

13.1.     Waste treatment methods

Waste treatment methods                     : Dispose in a safe manner in accordance with local/national regulations.

SECTION 14: Transport information                                                                                  

In accordance with ADR / IATA / IMDG





14.1.     UN number

Not applicable

Not applicable

Not applicable

14.2.     UN proper shipping name

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

14.3.     Transport hazard class(es)

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

14.4.     Packing group

Not applicable

Not applicable

Not applicable

14.5.     Environmental hazards

Not applicable

Not applicable

Not applicable

No supplementary information available

    1. Special precautions for user
  • Overland transport

Not applicable



  • Transport by sea

Not applicable

  • Air transport

Not applicable

    1. Transport in bulk according to Annex II of Marpol and the IBC Code

Not applicable


SECTION 15: Regulatory information                                                                                


    1. Safety, health and environmental regulations/legislation specific for the substance or mixture
      1. EU-Regulations

No REACH Annex XVII restrictions

Ferric-EDDHA is not on the REACH Candidate List Ferric-EDDHA is not on the REACH Annex XIV List

      1. National regulations Germany

Reference to AwSV                                                                                       : Water hazard class (WGK) 1, low

hazard to water (Classification according to VwVwS, Annex 3; ID No. 8485)


12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV



: Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance)


SZW-lijst van kankerverwekkende stoffen                                                       : Ferric-EDDHA is listed

SZW-lijst van mutagene stoffen                                                                      : Ferric-EDDHA is listed NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Borstvoeding   : The substance is not listed


NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Vruchtbaarheid


: The substance is not listed


NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Ontwikkeling    : The substance is not listed


    1. Chemical safety assessment

No additional information available


SECTION 16: Other information                                                                                         

Indication of changes:


Additional information




Log Kow


Fixed missing value


Bulk density




Abbreviations and acronyms:


Acute Toxicity Estimate


European Agreement concerning the International Carriage of Dangerous Goods by Road


Bioconcentration factor


Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008


Dangerous Preparations Directive 1999/45/EC


Dangerous Substances Directive 67/548/EEC




International Air Transport Association


International Maritime Dangerous Goods


Median lethal concentration


Median lethal dose


Lowest Observed Adverse Effect Level


No-Observed Adverse Effect Concentration


Persistent Bioaccumulative Toxic


Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation (EC) No 1907/2006


Safety Data Sheet

Data sources                                        : ECHA (European Chemicals Agency). Supplier. REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT and OF THE COUNCIL of

16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.


SDS Biochemicals version 2018

This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product





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