SAFETY DATA SHEET

Product Name                          Kojic acid

Cat No. :                                    A10760

CAS-No                                                    501-30-4

Synonyms                                                5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Recommended Use                              Laboratory chemicals.

Uses advised against                          Food, drug, pesticide or biocidal product use.

Details of the supplier of the safety data sheet

Company

Alfa Aesar

Thermo Fisher Scientific Chemicals, Inc. 30 Bond Street

Ward Hill, MA 01835-8099 Tel: 800-343-0660

Fax: 800-322-4757

Email: tech@alfa.comwww.alfa.com

Emergency Telephone Number

During normal business hours (Monday-Friday, 8am-7pm EST), call (800) 343-0660. After normal business hours, call Carechem 24 at (866) 928-0789.

 

 

Classification

This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Carcinogenicity                                                                                      Category 2

 

 

Label Elements

Signal Word

Warning

 

Hazard Statements

Suspected of causing cancer

Precautionary Statements Prevention

Obtain special instructions before use

Do not handle until all safety precautions have been read and understood Wear protective gloves/protective clothing/eye protection/face protection Response

IF exposed or concerned: Get medical attention/advice

Storage

Store locked up

Disposal

Dispose of contents/container to an approved waste disposal plant

Hazards not otherwise classified (HNOC)

Other hazards

May cause skin, eye, and respiratory tract irritation. May be harmful by inhalation, ingestion, or skin absorption.

 

 

 

General Advice                                      If symptoms persist, call a physician.

 

Eye Contact                                            Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

 

Skin Contact                                            Wash off immediately with plenty of water for at least 15 minutes. Get medical attention.

 

Inhalation                                                  Remove to fresh air. Get medical attention. If not breathing, give artificial respiration.

 

Ingestion                                                  Do NOT induce vomiting. Get medical attention.

 

Most important symptoms and effects

No information available.

Notes to Physician                                Treat symptomatically

Suitable Extinguishing Media              Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.

Unsuitable Extinguishing Media        No information available

Flash Point                                        No information available

Method -                                            No information available

Autoignition Temperature                    No information available

Explosion limit s

Upper                                                  No data available

Lower                                                No data available

Sensitivity to Mechanical Impact No information available

Sensitivity to Static Discharge    No information available

Specific Hazards Arising from the Chemical

Keep product and empty container away from heat and sources of ignition.

Hazardous Combustion Products

Carbon monoxide (CO). Carbon dioxide (CO2).

Protective Equipment and Precautions for Firefighters

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

NFPA

Health

2

Flammability

1

Instability

0

Physical hazards

N/A

Personal Precautions                          Ensure adequate ventilation. Use personal protective equipment as required. Avoid dust

formation.

Environmental Precautions                Should not be released into the environment. See Section 12 for additional Ecological

Information.

Methods for Containment and Clean Sweep up and shovel into suitable containers for disposal. Keep in suitable, closed

Up                                                              containers for disposal.

 

 

Handling                                                    Wear personal protective equipment/face protection. Ensure adequate ventilation. Do not

get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation.

 

Storage                                                    Keep containers tightly closed in a dry, cool and well-ventilated place.

8. Exposure controls / personal protection

 

 

Exposure Guidelines                            This product does not contain any hazardous materials with occupational exposure

limit sestablished by the region specific regulatory bodies.

 

 

 

Engineering Measures                          Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations

and safety showers are close to the workstation location.

 

Personal Protective Equipment

 

Eye/face Protection                        Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.

 

Skin and body protection              Wear appropriate protective gloves and clothing to prevent skin exposure.

 

Respiratory Protection                  Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limit s are exceeded or if irritation or other symptoms are experienced.

 

Hygiene Measures                          Handle in accordance with good industrial hygiene and safety practice.

Physical State                                                                                        Powder Solid

Appearance                                                                                            Beige

Odor                                                                                                        Odorless

Odor Threshold                                                                                    No information available

pH                                                                                                            No information available

Melting Point/Range                                                                              151 - 156 °C / 303.8 - 312.8 °F

Boiling Point/Range                                                                              No information available

Flash Point                                                                                              No information available

Evaporation Rate                                                                                  Not applicable

Flammability (solid,gas)                                                                      No information available

Flammability or explosive limit s

Upper                                                                                                No data available

Lower                                                                                                No data available

Vapor Pressure                                                                                    No information available

Vapor Density                                                                                        Not applicable

Specific Gravity                                                                                    No information available

Solubility                                                                                                  Soluble in water

Partition coefficient; n-octanol/water                                              No data available

Autoignition Temperature                                                                  No information available

Decomposition Temperature                                                            No information available

Viscosity                                                                                                Not applicable

Molecular Formula                                                                              C6 H6 O4

Molecular Weight                                                                                  142.11

 

 

 

Reactive Hazard                                    None known, based on information available

 

Stability                                                    Stable under normal conditions.

 

Conditions to Avoid                                Incompatible products. Excess heat. Avoid dust formation.

 

Incompatible Materials                        Strong oxidizing agents, Strong bases Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization                                        Hazardous polymerization does not occur.

Hazardous Reactions                          None under normal processing.

11. Toxicological information

 

 

Acute Toxicity

 

Product Information                              No acute toxicity information is available for this product

Component Information

Toxicologically Synergistic Products

No information available

delay ed and immediate effects as well as chronic effects from short and long-term exposure Irritation                                                    No information available

Sensitization                                            No information available

Carcinogenicity                                      Possible cancer hazard. May cause cancer based on animal data. The table below

indicates whether each agency has listed any ingredient as a carcinogen.

Mutagenic Effects                                  No information available

Reproductive Effects                            No information available.

Developmental Effects                        No information available.

Teratogenicity                                        No information available.

STOT - single exposure                        None known

STOT - repeated exposure                  None known

Aspiration hazard                                  No information available

Symptoms / effects,both acute and  delay ed

No information available

Endocrine Disruptor Information      No information available

Other Adverse Effects                          The toxicological properties have not been fully investigated.

Ecotoxicity

Do not empty into drains.

Persistence and Degradability          Soluble in water Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation        No information available.

Mobility                                                      Will likely be mobile in the environment due to its water solubility.

 

 

Waste Disposal Methods                    Chemical waste generators must determine whether a discarded chemical is classified as a

hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.

14. Transport information

 

 

DOT                                                            Not regulated

  TDG                                                          Not regulated

IATA                                                            Not regulated

IMDG/IMO                                                  Not regulated

15. Regulatory information

 

United States of America Inventory

 

Component	CAS-No	TSCA	TSCA Inventory notification - Active/Inactive	TSCA - EPA Regulatory Flags
5-Hydroxy-2-hydroxymethyl-4-pyro ne	501-30-4	-	-	-

 

Legend:

TSCA - Toxic Substances Control Act, (40 CFR Part 710)

X - Listed

'-' - Not Listed

 

TSCA 12(b) - Notices of Export            Not applicable

International Inventories

Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Philippines (PICCS), Japan (ENCS), Australia (AICS), China (IECSC), Korea (ECL).

U.S. Federal Regulations

SARA 313                                                Not applicable

SARA 311/312 Hazard Categories    See section 2 for more information

CWA (Clean Water Act)                        Not applicable

Clean Air Act                                            Not applicable

OSHA - Occupational Safety and Health Administration

Not applicable

CERCLA                                                    Not applicable

California Proposition 65                      This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

Not applicable

U.S. Department of Transportation

Reportable Quantity (RQ):                      N

DOT Marine Pollutant                            N

DOT Severe Marine Pollutant              N

U.S. Department of Homeland security

This product does not contain any DHS chemicals.

SAFETY DATA SHEET

Creation Date 26-Feb-2008                                    Revision Date 14-Feb-2020                                                    Revision Number 2

Product Name                          Kojic acid

Cat No. :                                    A10760

CAS-No                                                    501-30-4

Synonyms                                                5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Recommended Use                              Laboratory chemicals.

Uses advised against                          Food, drug, pesticide or biocidal product use.

Details of the supplier of the safety data sheet

Company

Alfa Aesar

Thermo Fisher Scientific Chemicals, Inc. 30 Bond Street

Ward Hill, MA 01835-8099 Tel: 800-343-0660

Fax: 800-322-4757

Email: tech@alfa.comwww.alfa.com

Emergency Telephone Number

During normal business hours (Monday-Friday, 8am-7pm EST), call (800) 343-0660. After normal business hours, call Carechem 24 at (866) 928-0789.

 

 

Classification

This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Carcinogenicity                                                                                      Category 2

 

 

Label Elements

Signal Word

Warning

 

Hazard Statements

Suspected of causing cancer

Precautionary Statements Prevention

Obtain special instructions before use

Do not handle until all safety precautions have been read and understood Wear protective gloves/protective clothing/eye protection/face protection Response

IF exposed or concerned: Get medical attention/advice

Storage

Store locked up

Disposal

Dispose of contents/container to an approved waste disposal plant

Hazards not otherwise classified (HNOC)

Other hazards

May cause skin, eye, and respiratory tract irritation. May be harmful by inhalation, ingestion, or skin absorption.

 

 

 

General Advice                                      If symptoms persist, call a physician.

 

Eye Contact                                            Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

 

Skin Contact                                            Wash off immediately with plenty of water for at least 15 minutes. Get medical attention.

 

Inhalation                                                  Remove to fresh air. Get medical attention. If not breathing, give artificial respiration.

 

Ingestion                                                  Do NOT induce vomiting. Get medical attention.

 

Most important symptoms and effects

No information available.

Notes to Physician                                Treat symptomatically

Suitable Extinguishing Media              Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.

Unsuitable Extinguishing Media        No information available

Flash Point                                        No information available

Method -                                            No information available

Autoignition Temperature                    No information available

Explosion limit s

Upper                                                  No data available

Lower                                                No data available

Sensitivity to Mechanical Impact No information available

Sensitivity to Static Discharge    No information available

Specific Hazards Arising from the Chemical

Keep product and empty container away from heat and sources of ignition.

Hazardous Combustion Products

Carbon monoxide (CO). Carbon dioxide (CO2).

Protective Equipment and Precautions for Firefighters

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

NFPA

Health

2

Flammability

1

Instability

0

Physical hazards

N/A

Personal Precautions                          Ensure adequate ventilation. Use personal protective equipment as required. Avoid dust

formation.

Environmental Precautions                Should not be released into the environment. See Section 12 for additional Ecological

Information.

Methods for Containment and Clean Sweep up and shovel into suitable containers for disposal. Keep in suitable, closed

Up                                                              containers for disposal.

 

 

Handling                                                    Wear personal protective equipment/face protection. Ensure adequate ventilation. Do not

get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation.

 

Storage                                                    Keep containers tightly closed in a dry, cool and well-ventilated place.

8. Exposure controls / personal protection

 

 

Exposure Guidelines                            This product does not contain any hazardous materials with occupational exposure

limit sestablished by the region specific regulatory bodies.

 

 

 

Engineering Measures                          Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations

and safety showers are close to the workstation location.

 

Personal Protective Equipment

 

Eye/face Protection                        Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.

 

Skin and body protection              Wear appropriate protective gloves and clothing to prevent skin exposure.

 

Respiratory Protection                  Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limit s are exceeded or if irritation or other symptoms are experienced.

 

Hygiene Measures                          Handle in accordance with good industrial hygiene and safety practice.

Physical State                                                                                        Powder Solid

Appearance                                                                                            Beige

Odor                                                                                                        Odorless

Odor Threshold                                                                                    No information available

pH                                                                                                            No information available

Melting Point/Range                                                                              151 - 156 °C / 303.8 - 312.8 °F

Boiling Point/Range                                                                              No information available

Flash Point                                                                                              No information available

Evaporation Rate                                                                                  Not applicable

Flammability (solid,gas)                                                                      No information available

Flammability or explosive limit s

Upper                                                                                                No data available

Lower                                                                                                No data available

Vapor Pressure                                                                                    No information available

Vapor Density                                                                                        Not applicable

Specific Gravity                                                                                    No information available

Solubility                                                                                                  Soluble in water

Partition coefficient; n-octanol/water                                              No data available

Autoignition Temperature                                                                  No information available

Decomposition Temperature                                                            No information available

Viscosity                                                                                                Not applicable

Molecular Formula                                                                              C6 H6 O4

Molecular Weight                                                                                  142.11

 

 

 

Reactive Hazard                                    None known, based on information available

 

Stability                                                    Stable under normal conditions.

 

Conditions to Avoid                                Incompatible products. Excess heat. Avoid dust formation.

 

Incompatible Materials                        Strong oxidizing agents, Strong bases Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization                                        Hazardous polymerization does not occur.

Hazardous Reactions                          None under normal processing.

11. Toxicological information

 

 

Acute Toxicity

 

Product Information                              No acute toxicity information is available for this product

Component Information

Toxicologically Synergistic Products

No information available

delay ed and immediate effects as well as chronic effects from short and long-term exposure Irritation                                                    No information available

Sensitization                                            No information available

Carcinogenicity                                      Possible cancer hazard. May cause cancer based on animal data. The table below

indicates whether each agency has listed any ingredient as a carcinogen.

Mutagenic Effects                                  No information available

Reproductive Effects                            No information available.

Developmental Effects                        No information available.

Teratogenicity                                        No information available.

STOT - single exposure                        None known

STOT - repeated exposure                  None known

Aspiration hazard                                  No information available

Symptoms / effects,both acute and  delay ed

No information available

Endocrine Disruptor Information      No information available

Other Adverse Effects                          The toxicological properties have not been fully investigated.

Ecotoxicity

Do not empty into drains.

Persistence and Degradability          Soluble in water Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation        No information available.

Mobility                                                      Will likely be mobile in the environment due to its water solubility.

 

 

Waste Disposal Methods                    Chemical waste generators must determine whether a discarded chemical is classified as a

hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.

14. Transport information

 

 

DOT                                                            Not regulated

  TDG                                                          Not regulated

IATA                                                            Not regulated

IMDG/IMO                                                  Not regulated

15. Regulatory information

 

United States of America Inventory

 

Component	CAS-No	TSCA	TSCA Inventory notification - Active/Inactive	TSCA - EPA Regulatory Flags
5-Hydroxy-2-hydroxymethyl-4-pyro ne	501-30-4	-	-	-

 

Legend:

TSCA - Toxic Substances Control Act, (40 CFR Part 710)

X - Listed

'-' - Not Listed

 

TSCA 12(b) - Notices of Export            Not applicable

International Inventories

Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Philippines (PICCS), Japan (ENCS), Australia (AICS), China (IECSC), Korea (ECL).

U.S. Federal Regulations

SARA 313                                                Not applicable

SARA 311/312 Hazard Categories    See section 2 for more information

CWA (Clean Water Act)                        Not applicable

Clean Air Act                                            Not applicable

OSHA - Occupational Safety and Health Administration

Not applicable

CERCLA                                                    Not applicable

California Proposition 65                      This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

Not applicable

U.S. Department of Transportation

Reportable Quantity (RQ):                      N

DOT Marine Pollutant                            N

DOT Severe Marine Pollutant              N

U.S. Department of Homeland security

This product does not contain any DHS chemicals.